Ellansé PCL Fillers

by Artisan

10,000+ Artisanal PCL Filler Results

Where Expertise Meets Artistry

50+ Years of Combined
Doctor Experience

In Aesthetic & Regenerative Medicine

8 Specialist Clinics

Across the Artisan Group

10,000+ Artisanal PCL Filler Results

Where Expertise Meets Artistry

50+ Years of Combined
Doctor Experience

In Aesthetic & Regenerative Medicine

8 Specialist Clinics

Across the Artisan Group

Over 10,000 PCL Filler in 
Artisan Clinic Singapore

— A Popular Collagen-Stimulating Fillers

PCL fillers represent a different approach to facial rejuvenation in aesthetic medicine. While traditional dermal fillers primarily work by replacing lost volume, PCL (polycaprolactone) fillers take things a step further by stimulating the skin's own collagen production — supporting improvements in firmness, texture, and overall skin quality that develop gradually over time.

Across Asia, including Taiwan, China, and Singapore, PCL fillers have seen growing interest among individuals who prefer collagen restoration and skin quality improvement over more dramatic volumetric changes. This shift reflects a broader move towards treatments that work with the body's natural processes.

At Artisan Clinic Singapore, our doctors are trained in refined injection techniques, ensuring that PCL fillers are delivered with precision and care — working with your natural facial structure to maintain harmony and balance.
Whether your concerns involve fine lines, skin laxity, or long-term collagen health, PCL fillers offer a clinically backed approach that works gradually with the body's own renewal processes.
In the sections below, we cover how PCL fillers work, their key characteristics, and their role in collagen-based facial rejuvenation in Singapore.

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What Is PCL Filler (少女针)?

PCL fillers — commonly known as 少女针 in Chinese — go a step beyond traditional dermal fillers by supporting the skin's natural renewal process. Rather than simply replacing lost volume, PCL fillers stimulate collagen production from within, addressing common signs of ageing such as sagging, fine lines, and reduced firmness.


The treatment consists of polycaprolactone (PCL) microspheres suspended in a gel carrier. The gel provides initial volume and contour, while the PCL microspheres gradually activate the skin's collagen-building processes over the following months. This dual action offers both an immediate volumising effect and progressive skin strengthening — with results that can be sustained over an extended period.


Unlike conventional fillers that primarily address volume loss, PCL fillers work as a collagen stimulator — encouraging the skin to rebuild its own structure and elasticity for outcomes that develop naturally over time.

How Does PCL Filler (少女针) Work?

PCL filler works in two stages — providing an initial volumising effect and long-term collagen stimulation for results that develop naturally over time.

01

PCL Microspheres Collagen Stimulation

A key component of this treatment is polycaprolactone (PCL) microspheres, which function as a biostimulator. Once injected, these biodegradable microspheres work to encourage collagen production in the treated area. This process occurs not only in the deeper layers where the filler is placed but also in the surrounding dermis, contributing to:

Improved Skin Quality

— Firmer, smoother, and more elastic skin over time.

Long-lasting lift and volume

— Effects that continue to improve over the following months and can last several years.

02

CMC Gel — Initial Volume & Lift

While collagen takes time to rebuild, the carboxymethylcellulose (CMC) gel component provides an initial volumising effect. It helps lift and restore volume to areas of concern, offering a refreshed appearance shortly after treatment — even before the collagen stimulation process begins.

03

Artisan Techniques for Natural Results

When performed with refined technique and a holistic approach, PCL filler can create a subtle, naturally lifted appearance. At Artisan Clinic Singapore, our doctors focus on working with your facial contours rather than overfilling, aiming for a refreshed look that still looks like you.This two-phase effect — initial volume combined with long-term collagen rebuilding — is what makes PCL filler a valued option for those seeking gradual, natural-looking improvement.

The PCL Filler (少女针) Difference

Exceptional Safety Record

PCL fillers have been studied across multiple clinical trials. In one systematic review involving over 1,100 patients, more than 83% experienced only mild, short-lived side effects, with no reports of serious complications including vascular injuries (ResearchGate). A separate multicenter study that followed patients for up to 30 months also reported no severe adverse events, supporting PCL's profile as a well-tolerated option over the longer term (ResearchGate).

High G′ (G-prime) – Built for Lifting

This filler is recognised for its high G′ (firmness), which provides structural support beneath the skin. This property allows it to lift and contour areas such as the cheeks, jawline, chin, and nose — functioning similarly to a soft-thread lift, with results that settle naturally over time.

Cohesive, Stable Fill for Controlled Placement

PCL filler is cohesive, meaning once placed, it stays in position — unlike some conventional fillers that may spread or shift over time. This makes it well-suited for mobile areas of the face, such as the smile lines and cheeks, where precise placement is important for a balanced outcome.

Why It Stands Apart from Traditional HA Fillers

PCL Filler (少女针)

Typical HA Fillers

COLLAGEN STUMULATION

YES —Gradual, long-lasting

No — Temporary filler only

LIFT AND VOLUME

Strong and structural

Softer, dissolves faster

MIGRATION

Minimal (cohesive)

Can shift over time

LONGEVITY

1-3+ years

6-12 months

Bottom line: PCL filler offers a clinically validated safety profile, powerful lifting capacity, and reliable positional stability. It’s a refined collagen stimulator that sculpts with control—ensuring results look natural and balanced.

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Who Is PCL Filler (少女针) For?

PCL filler goes beyond volume replacement — it supports reshaping, lifting, and restoring facial structure in a way that develops naturally over time. It is well-suited for individuals seeking long-lasting, collagen-stimulating outcomes tailored to their unique facial anatomy.

Sunken or Aged Faces

For those experiencing volume loss that leaves the face looking tired or hollow, PCL filler works by encouraging collagen production from within the skin. It helps address hollow areas such as the temples, cheeks, and under-eyes, while also contributing to improvements in overall skin texture. Over time, patients may observe a reduction in wrinkles, fine lines, and uneven skin tone as collagen renewal takes effect.

Sunken or Aged Faces

When the lower face begins to lose its support structure — leading to nasolabial folds, marionette lines, and jowls — traditional fillers alone may not fully address the concern. PCL filler, combined with strategic injection techniques, can create a lifting effect similar to a thread lift by targeting key support points across the face, without resulting in a puffy or overdone appearance.

Sunken or Aged Faces

PCL filler is a suitable option for those looking to improve facial balance and structure. It can be applied along the jawline, chin, and nose to subtly refine these features, working towards a more defined and proportionate facial profile. The goal is to enhance structure while preserving the face's natural softness and character.

Sunken or Aged Faces

A common assumption is that fillers aren't suitable for fuller or rounder faces — especially those that may already appear overfilled from previous treatments. However, with a methodical sculpting approach, PCL filler can be used to contour and define facial features, bringing more structure and balance to rounder face shapes.

How Much PCL Filler (少女针)  Do You Need?

The amount of PCL filler used varies from person to person, depending on:

Common Myths About PCL Filler (少女针)

Myth 1
“PCL filler will make my face look overfilled. 🧐“

Overfilled results can occur when a treatment is not well-planned. At Artisan Clinic Singapore, our doctors strategically place the filler to balance volume, lift at the right support points, and work towards a natural-looking outcome. With proper placement and technique, the same amount of filler can produce a well-balanced result.

Myth 2
“I already have a full, round face — won't this make it worse? 🧐”

Not necessarily. When injected with a sculpting and lifting approach, PCL filler can help define and contour the face by restoring support and lifting sagging tissues. The focus is on reshaping, not just adding volume.

BOOK AN APPOINTMENT

At The Artisan Clinic, all our doctors are well-trained professionals.

We keep ourselves up to date with latest trends and updates in the Aesthetic medicine field by being constantly involve and participating in seminars and conferences around the world.

Our Medical Director, Dr. Isaac Wong is an international trainer, and is often invited to speak in international conferences.

All treatments by The Artisan Clinic doctors are carefully curated by our Medical Director, Dr. Isaac Wong.

Long lasting

Ellansé maintains volume better over time.

Safe to use

Ellansé has better sculpting properties for the chin, forehead and nose.

Extra benefit

Ellansé fillers encourage bio-stimulation of collagen growth.

Cost effective

Unlike normal fillers, Ellansé fillers are a lot more long lasting, thus they are more cost effective in the long run.

Static and dynamic content editing

Long lasting

PCL maintains volume better over time.

Safe to use

PCL has better sculpting properties for the chin, forehead and nose.

Extra benefit

PCL fillers encourage bio-stimulation of collagen growth.

Cost effective

Unlike normal fillers, PCL fillers are a lot more long lasting, thus they are more cost effective in the long run.

Frequently asked questions

Aging is inevitable but you can choose to age gracefully.

Naturally healthy skin

Rid your skin problems, wake up to beautiful clear skin.

Enhance facial contours

Get features you want with injectables that looks natural.

Thicker, fuller hair

Counter hair loss medically with our doctor-designed treatments.

Restore youthful looks

Reduce your skin age appearance by years.

Fair and dewy skin

Say hello to skin that looks like you have make up on.

Body slimming

Using FDA-approved machines to help you slim down faster.

Dr. Isaac Wong

MBBS (Singapore), AAAM

Beauty Reborn At The Artisan Clinic Everyday

This article has been medically reviewed by Dr Isaac Wong.

Dr Isaac Wong is the Founder and Medical Director of The Artisan Clinic, an international trainer in aesthetic medicine. Dr Isaac Wong's work in injectables, threadlifts, and energy-based devices has led to invitations as a speaker at global conferences and appointments as a regional trainer for some aesthetic brands.

Let us transform you.

Recapture your beauty and witness the power of transformation at The Artisan Clinic. What are you struggling with now?

Please indicate your current problem or share any other remarks for us to note before your appointment.

Let's start your journey of transformation.

Your submission has been received.
Your submission has been received. Our customer representative will contact you soon! For quicker response, please call us at +65 8879 7887
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Over 10,000 Ellansé Fillers done at The Artisan Clinic.

Our doctors at The Artisan Clinic have over 20 years of combined experience. A ‘less is more’ treatment philosophy is adopted that aims for natural looking results — no puffy pillow faces please!

Ellanse Lady Heart Protocol

Outer Contour Lifting 少少女心外轮廓提升

Unlike other fillers in Singapore, Ellansé is a filler which contains collagen stimulation properties and does not use hyaluronic acid as its main component.

The main component of Ellansé fillers is Poly-Caprolactone (PCL), a type of long lasting polymer that your body can absorb naturally over time. With the use of collagen, Ellansé fillers restore volume to the skin as well as lifting it and making it look healthier.

Our Medical Director, Dr. Isaac Wong, is an international trainer for Ellansé and has worked with many celebrities in Singapore.

WHAT IS ELLANSÉ

How does Ellansé fillers work?

The inevitable effects of aging is a loss of collagen and elastin within the dermis. As we age, our skin, fat and muscles in our face slowly degenerate. Sagging skin, wrinkles, eye bags, sunken temples. These are all signs of aging that can make us look weary and haggard.

Ellansé fillers contains polycaprolactone (PCL), a bioresorbable medical polymer that stimulates neocollagenesis. This process allows your skin to naturally produce collagen over 3-6 months, which fights against and slows down the effects of aging.

Used Ellanse Syringes by Dr Isaac Wong at The Artisan Clinic.

Benefits of Ellansé fillers in Singapore

Ellansé has an advantage whereby a single* session is enough to correct and rejuvenate (*depending on the lack of tissue and ageing of the skin). The administration process is totally pain-free with local anesthetic injection or application of anesthetic cream.

  • Restoring volume to the face
  • Reducing the appearance of dark eye circles
  • Contouring the nose bridge
  • Enhancing chin and jawline definition
  • Stimulating collagen growth
  • Reducing facial aging

The Ellansé filler difference

Unlike traditional hyaluronic acid-based fillers which address signs of aging like fine lines and wrinkles by filling up lost volume, Ellansé fillers directly reverses the underlying causes of ageing, resulting in longer lasting results.

Continuous stimulation of your body's natural collagen production after procedure.
Dr Isaac Wong & The Artisan Clinic was awarded the Top Ellanse Clinic 2022 and Top 50 APAC Clinics by Sinclair Pharma CEO, Miguel Pardos in July 2023.
WHO IS Ellansé FOR
  • Ellansé fillers help individuals in Singapore which are looking to tackle the underlying causes of ageing and restores your youthful appearance by:
  • You are suitable for Ellansé fillers if you:
  • Want to restore youth to your face
  • Dislike yearly filler injections
  • Have signs of facial ageing but are not keen on a surgical facelift
  • Want rejuvenated, younger looking skin

Ellanse Lady Heart Protocol

Outer Contour Lifting 少少女心外轮廓提升

Dr Isaac Wong

Founder, Medical Director of Artisan Medical Group, Singapore

Aesthetic Physician with interest in aesthetic procedures and regenerative medicine

  • Accredited Ellanse & Silhouette Soft Trainer (2016)
  • Accredited Maili Trainer (2024)
  • WEM Barcelona Before After Picture Prize Winner 2018
  • Sinclair China Injector, Trainer, Speaker (2024-)
  • Sinclair China Ellanse 2.0 Launch Guest Speaker 2024
  • Sinclair China Maili Launch Speaker 2025

Past Appointment: Asia Ellanse Advisory Board Member 2016

Scientific Publications

  • Hairline Polycaprolactone Injections for Facial Lifting: An Anatomical-Based Approach (ELLANSE)
  • Esthetic Correction of Lying Ears With Hyaluronic Acid Filler(MAILI)
  • Anatomy-Based Filler Injection Techniques for the Forehead (ELLANSE, MAILI)
  • Anatomical-Based Diagnosis and Filler Injection Techniques : Nasolabial Folds (MAILI)
  • Correction of Facial Asymmetry Using Dermal Fillers (MAILI) : Understanding the Role of Facial Rotation
  • Anatomical Considerations and Technique for Nasolabial Fold Thread Lifting
  • Non-Invasive Midface Rejuvenation via Low-Energy High-Intensity Focused Ultrasound : Two Case Reports of Buccal Fat Stem Cell Activation
  • The SIBUS-IN Fingerheld Ultrasound Machine
  • Advancements in Clinical Utilization of Recombinant Human Collagen: An Extensive Review
  • Taurus Philtrum: A Newly Identified Phenomenon in Overfilled Syndrome
  • Neurotoxin Modulation of Alar Band Dynamics
  • Optimizing Botulinum Toxin Injections in the Platysma Muscle Based on Motor Nerve Distribution
  • Lactobacillus-Derived Exosome Therapy for Active Acne Vulgaris, Post-Inflammatory Hyperpigmentation, and Atrophic Scarring
  • Efficacy and Safety of High-Intensity Focused Ultrasound (HIFU) on Reduction of Unwanted Submental Fat in Asian Patients
  • Exosome-Based Topical Therapy for Facial Atopic Dermatitis

Facial Aesthetics and Aging

For certain medical aesthetic items mentioned in this document, based on product-specific characteristics, please reference and apply them in accordance with the approved indications of the products within your respective jurisdictions.

Happens in all 5 layers of the face1,2,3

1. Mendelson BC, Wong CH. Anatomy of the aging face. Ch. 6. Volume 2 Aesthetic. In: Warren RJ, Neligan PC, eds. Plastic Surgery. 3rd ed. Elsevier; 2013:79–92

2. Fritz E B, Aesthetic Surgery of Face and Neck. Aesthet Sur J;29:449-463

3. Wong CH, Mendelson B. Newer Understanding of Specific Anatomic Targets in the Aging Face As Applied to Injectables : Aging Changes in the CranioFacial Skeleton and Facial Ligaments. Plast. Reconstr. Surg. 136:44S, 2015

  • InferolateralOrbit
  • Maxilla+++
  • Mandible

Fig. 2. The areas of the facial skeleton that selectively resorb with aging, with the size of the arrows indicating relative tendency for bone loss. These locations are the areas that should be specifically targeted for the use of injectables for skeletal augmentation. Reprinted with permission from Dr. Bryan Mendelson & Dr. Chin-Ho Wong from Changes in the Facial Skeleton with Aging: Implications and Clinical Applications in Facial Rejuvenation.Aesth Plast Surg (2012) 36:753–760. ©2012 Mendelson, Wong.

Retrusion,sagging of overlying soft tissue1,2,3

Fig. 1. The facial skeleton resorbs significantly with aging. This loss of support from the “foundation” of the face results in retrusion and “sagging” of the overlying soft tissues. Reprinted with permission from Dr. Bryan Mendelson & Dr. Chin-Ho Wong from Changes in the Facial Skeleton with Aging: Implications and Clinical Applications in Facial Rejuvenation.Aesth Plast Surg (2012) 36:753–760. ©2012 Mendelson, Wong.


1.MendelsonBC, Wong CH. Anatomy of the aging face. Ch. 6. Volume 2 Aesthetic. In: WarrenRJ, Neligan PC,eds. Plastic Surgery. 3rd ed. Elsevier; 2013:79–92

2.FritzE B, Aesthetic Surgery of Face and Neck.AesthetSur J;29:449-463

3.WongCH, Mendelson B. Newer Understanding of Specific Anatomic Targets in the AgingFace As Applied to Injectables : Aging Changes in the CranioFacialSkeleton and Facial Ligaments. Plast. Reconstr.Surg. 136:44S, 2015

Three-dimensionalfascial system → Connective tissue → Dense type I collagen

Fascia manifests in region- andfunction-specific forms, categorized anatomically into: true ligaments, falseligaments, skin retaining ligaments, septa, and fusion zones, etc

Continue reading about Lady Heart Injection Technique by Dr Isaac Wong

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At The Artisan Clinic, all our doctors are well-trained professionals.

We keep ourselves up to date with latest trends and updates in the Aesthetic medicine field by being constantly involve and participating in seminars and conferences around the world.

Our Medical Director, Dr. Isaac Wong is an international trainer, and is often invited to speak in international conferences.

All treatments by The Artisan Clinic doctors are carefully curated by our Medical Director, Dr. Isaac Wong.

Long lasting

Ellansé maintains volume better over time.

Safe to use

Ellansé has better sculpting properties for the chin, forehead and nose.

Extra benefit

Ellansé fillers encourage bio-stimulation of collagen growth.

Cost effective

Unlike normal fillers, Ellansé fillers are a lot more long lasting, thus they are more cost effective in the long run.

Static and dynamic content editing

Long lasting

Ellansé maintains volume better over time.

Safe to use

Ellansé has better sculpting properties for the chin, forehead and nose.

Extra benefit

Ellansé fillers encourage bio-stimulation of collagen growth.

Cost effective

Unlike normal fillers, Ellansé fillers are a lot more long lasting, thus they are more cost effective in the long run.

Frequently asked questions

Aging is inevitable but you can choose to age gracefully.

Naturally healthy skin

Rid your skin problems, wake up to beautiful clear skin.

Enhance facial contours

Get features you want with injectables that looks natural.

Thicker, fuller hair

Counter hair loss medically with our doctor-designed treatments.

Restore youthful looks

Reduce your skin age appearance by years.

Fair and dewy skin

Say hello to skin that looks like you have make up on.

Body slimming

Using FDA-approved machines to help you slim down faster.

Dr. Isaac Wong

MBBS (Singapore), AAAM

Beauty Reborn At The Artisan Clinic Everyday

This article has been medically reviewed by Dr Isaac Wong.

Dr Isaac Wong is the Founder and Medical Director of The Artisan Clinic, an international trainer in aesthetic medicine. Dr Isaac Wong's work in injectables, threadlifts, and energy-based devices has led to invitations as a speaker at global conferences and appointments as a regional trainer for some aesthetic brands.

Let us transform you.

Recapture your beauty and witness the power of transformation at The Artisan Clinic. What are you struggling with now?

Please indicate your current problem or share any other remarks for us to note before your appointment.

Let's start your journey of transformation.

Your submission has been received.
Your submission has been received. Our customer representative will contact you soon! For quicker response, please call us at +65 8879 7887
Oops! Something went wrong while submitting the form.